%PDF-1.4
%
219 0 obj
<>>>
endobj
216 0 obj
<>stream
doi:bmjopen-2019-035730
application/pdf
2020-01-31T10:22:30Z
2024-03-31T20:49:35-07:00
2024-03-31T20:49:35-07:00
Adobe InDesign CS6 (Windows)
uuid:5d2e295e-1dd2-11b2-0a00-8100a8009fff
xmp.did:B2C59A163194E611BD009A7CB80B8EC7
xmp.id:4AF84D961344EA11873CD6CD48BB3BFD
proof:pdf
xmp.iid:34820A941344EA11873CD6CD48BB3BFD
xmp.did:12BEE6AC550DE8118634A2E26D244B8E
xmp.did:B2C59A163194E611BD009A7CB80B8EC7
default
converted
from application/x-indesign to application/pdf
Adobe InDesign CS6 (Windows)
/
2020-01-31T10:22:30Z
d64fa1c1-2a9d-4521-a7f2-a78f1bce036e
Adobe PDF Library 10.0.1
False
endstream
endobj
220 0 obj
<>
endobj
177 0 obj
<>
endobj
215 0 obj
<>
endobj
221 0 obj
<>/Font<>/ProcSet[/PDF/Text]/Properties<>/Shading<>/XObject<>>>/Rotate 0/TrimBox[0.0 0.0 595.276 793.701]/Type/Page>>
endobj
1 0 obj
<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/TrimBox[0.0 0.0 595.276 793.701]/Type/Page>>
endobj
21 0 obj
<>/Font<>/ProcSet[/PDF/Text/ImageC]/XObject<>>>/Rotate 0/TrimBox[0.0 0.0 595.276 793.701]/Type/Page>>
endobj
38 0 obj
<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/TrimBox[0.0 0.0 595.276 793.701]/Type/Page>>
endobj
40 0 obj
<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/TrimBox[0.0 0.0 595.276 793.701]/Type/Page>>
endobj
49 0 obj
<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/TrimBox[0.0 0.0 595.276 793.701]/Type/Page>>
endobj
60 0 obj
<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/TrimBox[0.0 0.0 595.276 793.701]/Type/Page>>
endobj
81 0 obj
<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/TrimBox[0.0 0.0 595.276 793.701]/Type/Page>>
endobj
82 0 obj
[83 0 R 84 0 R 85 0 R 86 0 R 87 0 R 88 0 R 89 0 R 90 0 R 91 0 R 92 0 R 93 0 R 94 0 R 95 0 R 96 0 R 97 0 R 98 0 R 99 0 R 100 0 R 101 0 R 102 0 R 103 0 R 104 0 R 105 0 R 106 0 R 107 0 R 108 0 R 109 0 R 110 0 R 111 0 R 344 0 R]
endobj
341 0 obj
<>stream
HWko]S!a>RMb$xbDZo{pHJv9wN
F#F}Vhc>//X0qG3o烟848zyU1<8 VG~1Lrp3~Əzc0rC6#zs)rXhm}MsGqUt.~~?:e^z"./{`%Nuy|JoDqd3
f0a
8 n86\j+N*E&Wr)c^I|U,YZЛJI8ɉ}7`WR}<.f߲5RERp6_H41?¦1sE>ZR MUZHվ(eq묤OքZNQ+Oj2JXUPPb!(JՂ:Yq[']2jXa[+Yq!Dn+L//es¾_Uǜ-ybz qAee~'lrR0(4afUdVyEaMcxC2Ĉi#TWue]i.ѫ6Sn&3tgͦs4j]~v!!H&G_ewYg秧c( yק\4}\/c41qwX"6#>g3s:B+ó-/ HE&s^=XY㠃v+D{*rF5F9AB2E
=}0$<佬]OJ%DzRVkBFYGЕ=Hy7O@r|.MP쌽^Z)h*֪Wk$GRA#a'vv]RIMX{^V^TFy$m7e1+SνnƐ`Sqm
)dRڊ&DL"YMTNΝsw뼠uZ4)PdƕF)-/6!Pf<(c4neeט+E5j%+F"x+uEHSw
Ih'\UJeXP6 !ܦ̨0cdeNgR6 -(_J-mh6Eč؏*%H+Ǜd7Hjpn
]
=o"PF|QT*Ձj?veALS(i͘zşR6"N0?ݡНDcm'#|q~x|pO#;0'~Sݯq9X\SDF?}ca<6;
{gAiP7q
b}u^?8¨;!|e7cνL4x뀍2tc
e:Xp
ma-a7I8vBj"l"ͻu@WۡE\4UqU-" B P6
(fH NHds__YYfB=B?\z}6d˭c!f9i5Fb&9jt'"Goe^ct$Yꔶ[~ʙPvɩ"y]]Vyro:#ZT]ׯO$FNnKrʳr!Ҵ7yw'!F*ݏO[vZAL|k"&) ym-Ksq^I`5#w) S|aSX0a ~~6,joM'}t{U {nۗwgȎ5-Wy~Pa2`IN2Yѳ#Rtt7(c
$j7i'ޝk,anZh'c{udYu[ۉvn!k&Yggײ1^4oxO90I(OD,)ǺD(bm X;<ٖ
z)k9yy-aŨNDZ;U;-<){g?|K'`:
j6ý}늈蕹0+K!9Kʢ[l l_L(`s)u"+lf)W+GKHXy8IA䆓x'J̲`Ƥ{otE3(]/IׅA%%5bEf; -fs3,%ӣGR۲GpkxlF=> <}..k)"(UaE%!gsl#7Tq)ѯ7YY"
( #Ry39p梱kY~;Bl#ߎ͕q{"镆44=Ϸ\LFn4^B7`U6 g7n0SQa\ɳywܠ]8
#wэslǕ Kn)x%|.rGc蹳)xm,x;1L A$;^;M3mҌ4[Rzi
%\\{GnQA^| @Q)*/D-ԕ"Ql6&N0eXjP+a5[s9!ܶėϋ?^7.
UZFc8rg++0!>*$lQ_iHhvʙhZeE LeIH`J\cQ12xoA*%) #M
aHU1su\s5~O)| .D&Z/*;=e":ȋ\5jz?=[..ȿBhlq:_Rg+e ڼ.z_i.jMYW1587}MΊGdL::Гw1
.Dæw^mJ
=<=ɮu_jazlmuv1Z, &^CAy |}`NC[$uKaEuїoAAO1ʎs,;3/';Q(NU
dfNV{Xf֓#I%)Źy0URUb;#L7)Ǩhltq]v
r,8`M]i CȞ_DT0E|Ij
fDxuR)NXtս3Tee]AzOF[,&_(#88AsjGSe8ix}a9x |Z45> LV[g&d@!2J$>.ǯ/S8{(aKTtce}")FSWoƅCOk
("d:L%E*Jj..t ^\}L3WY^^tz([>1\g7; a7~>n V]V[}8S4^'Qm@QO60 Cĥ\*!m<2M]ʥ]xYY<8N]Zj
xZk:Jp#7U
V{k>ש ˓v0 PQ!mSF`:]XjQOrS`8ʘtMA]sv~E(}l[u2S<"&:"/G4w]{6
j)ǟIO'&edq?r'O(VMG`;R.40_tbnITOad:{^Qî+32b`Y'arwd|tAn7A -hC1}vZerٷ_kE/FF\ >xbnH=
}kBdg7!Lt;r]{8lhce$&EPGJ9%?cXݮ"a7u~nHEt;1>V%Q@rD[M,`; ЗտW>äؽlO2\*?\+5$9T2goWN:\t֝E5&boC/?,:{I
X!*J
Pqc TQ_60O">f-Ψ0Kf>ؘϱ@nuRra-%8%ɻ{0^Kda\9ԫ l8l5}@05ͯL#hL|s1ge"'hfr_d;mmۏpV bs:hT