%PDF-1.5
%
321 0 obj
<>>>
endobj
318 0 obj
<>stream
doi:bmjopen-2017-019189
application/pdf
2021-01-05T12:53:30Z
2024-10-29T00:54:45-07:00
2024-10-29T00:54:45-07:00
Adobe InDesign CS6 (Windows)
uuid:2a82e740-1dd2-11b2-0a00-9000e800a2ff
xmp.did:B2C59A163194E611BD009A7CB80B8EC7
xmp.id:99355AFC544FEB11A341FC7A13FCA2F1
proof:pdf
xmp.iid:98355AFC544FEB11A341FC7A13FCA2F1
xmp.did:12BEE6AC550DE8118634A2E26D244B8E
xmp.did:B2C59A163194E611BD009A7CB80B8EC7
default
converted
from application/x-indesign to application/pdf
Adobe InDesign CS6 (Windows)
/
2021-01-05T12:53:30Z
1ec41e17-7c87-46ed-9872-41323bc55f52
Adobe PDF Library 10.0.1
False
endstream
endobj
322 0 obj
<>
endobj
287 0 obj
<>
endobj
317 0 obj
<>
endobj
323 0 obj
<>/Font<>/ProcSet[/PDF/Text]/Properties<>/Shading<>/XObject<>>>/Rotate 0/TrimBox[0.0 0.0 595.276 793.701]/Type/Page>>
endobj
1 0 obj
<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/TrimBox[0.0 0.0 595.276 793.701]/Type/Page>>
endobj
44 0 obj
<>/Font<>/ProcSet[/PDF/Text/ImageC]/XObject<>>>/Rotate 0/TrimBox[0.0 0.0 595.276 793.701]/Type/Page>>
endobj
65 0 obj
<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/TrimBox[0.0 0.0 595.276 793.701]/Type/Page>>
endobj
90 0 obj
<>/Font<>/ProcSet[/PDF/Text/ImageC]/XObject<>>>/Rotate 0/TrimBox[0.0 0.0 595.276 793.701]/Type/Page>>
endobj
96 0 obj
<>/Font<>/ProcSet[/PDF/Text/ImageC]/XObject<>>>/Rotate 0/TrimBox[0.0 0.0 595.276 793.701]/Type/Page>>
endobj
113 0 obj
<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/TrimBox[0.0 0.0 595.276 793.701]/Type/Page>>
endobj
174 0 obj
<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/TrimBox[0.0 0.0 595.276 793.701]/Type/Page>>
endobj
175 0 obj
[176 0 R 177 0 R 178 0 R 179 0 R 180 0 R 181 0 R 182 0 R 183 0 R 184 0 R 185 0 R 186 0 R 187 0 R 188 0 R 189 0 R 190 0 R 191 0 R 192 0 R 193 0 R 194 0 R 195 0 R 196 0 R 197 0 R 198 0 R 199 0 R 200 0 R 201 0 R 202 0 R 203 0 R 204 0 R 205 0 R 206 0 R 207 0 R 208 0 R 209 0 R 210 0 R 211 0 R 212 0 R 213 0 R 214 0 R 215 0 R 216 0 R 217 0 R 218 0 R 219 0 R 450 0 R]
endobj
447 0 obj
<>stream
Hms2GDIHX3G|uW~X{pI弩+8d_>I@? -4~Ad¶~sc5NMӍQ@?a27}Lq5hEOML?5]fbu{ƨqa3)EAk -&uP\f4S a^p'Yߞy{?7ֳ<\.SU3I>_<2.jGI)ncy}.K̳'TPZm|7D˙%~9vem;&o[pDAG
rj̍ǪHyA"rRjXAICU!8ճ(K19RR[#)24t58wQ+fM%9LDCӵ 5=6o~0U
g3" Ӕ7;!!R-p)_Fo-αHL8N]ܤ%_%tF0)X7Q2̚]Fc܂6mi
=D+LtE 6
<=,BV*<&t3TCtaAE`Ĺr0dAGAEsH=5 kLBE:ujXĦ 4;ˤYu4ݭ=ȊǮs2i81N^0ߴׅ=i0? JZiXU>Sށ,F4ݸC?9|UPh(O!Ζ^A,{=naJ "%\<~\HANɪ
/"j6%_yk_<Ȗ/=KtU="CRq/{f᎒Y)VaF8ǀ*ъ*2 , )88@)\WMHI,8a\${,jyEnJz̴$7T19yTA,,Ѽwc4f
ϰ2&S2[S1`ed8amn$s5=jIw#q^`xO
<Ўݝ}7u\G1#z7S:j8HGQ0GT>j8>+ۑh
Ņ8
4_*c6ОUVpF4Xu|8/8`؞ͺ<<m.}n[Ϣ 7-c=I\ZpR1ܴDžUL.MaKW1n
L+Mgim5^N{40ʣ4e?N,ʃ~=j(Ґi8uhX|4!a֬?L-7TC?/t -j (mv"ceB/D
BX-(:/j[σ8UzE:z[CűAsF>41N[!ɰzQbVF90M;#6sM{8iΜ=s%3-%
:er&]Q.Q֩bWbw+mvmsuݭb6v_.Xj)p>m-clzS2^}dJHkDj鯒֦ ' \:/$b.DX*VDCUZ6Ҧ*1ƾ^[9mjz{ D-\ֶWws8,HʲEYp-ewki1
Q`쇥f۪?DU0ka>VsRv<ȕfP,e*Ã =Zw*m'L˗&qj6
Xa!y[4oK"OCF)8Z^wc]nuTN
uO!l5I}PeISZ1V~Oי;O0-IH4/շ-{k.MX!Jo Ng^e 5H/hAޢFVm8QhdX@MQAHZHD$?oWWzݝs*v+ĠuɄMKvwGUwcp cIwSzWw9v\G({'RmV4U5@S驅P[ V K.Kma1R(sɁj XO-mlPP`.q4QF)eiô\\1XĤ_3YѬ缬'LȦRר~-7:rvG Bif}Hכ:i2
ۿ']G'ɂ҄~)fGL5q+9n91)~GbFY'הmcڂO:gr|x4pU͏~ii]N!;_}q扽5#,Jg}
`Ԡ>>DžtyR{'0(B)WۅQI3<{mfmp:FAmt8ݓyʾ+w[ٕq cvq
DS)~?(^ܔC$K9ӌ.&g"V&*\_'ǓᘭJŤdj`/d6O$J~D5m\;MR#]wLrLewTѽ0i.u3-'Wr'rwk(VLa.>7p\dtX%l#OLR͒<`=տ\$3Ob"|އ#4Rw>;Gjx sNִ=jm0zq$#$݄\FtzB)~ d]RdiPH#
LF]
ېSB]aKdFk$f83?g%OHI(
m[*S[ⵗ.w:^Q2eyPYQ0שNΰHynG>u"a=E.MbCsa\Cx-#D7$A(\a&꺴!t3r?vj>(Ym)$+m\꽁*~w~l a9Z!aJ0/2c72*`̮Y2ThHf;Ok6 HȂ5{5rpʸZaaes.-<=2`
#GnWhjT _^2ip˴Y)Hf}|x8R:iQ-trg-ܬ2hqF6+euFͺ>Z@MˍJ0F::QL2?&z \?ĩ[ZS^$}h9Xz}5ҏSh8Xwl
E6qC:;
7`f{-aHxM *=c~Z4 /c4a \L_!%'~0At-7Msdc]3'+,B> Bn}aFOA[ӣ;d.NI}lh]mMď%@SU `b}}SHY8͓tf~f>uI[WժqI`"ɕEB0{V<%#g煘=?`=2ܱ!uF$
kaQMbH'bxm&'O\=0ONV,ī]
O_(Qz29(mHM \숇aSvX}@>C%̓,˺sr,T4nfIL[tc1hO3\_NkUHWۼTGe%Yor˴tQmjAEyD%n xq,C
Jt!ߞF/UB;`m ,;v]1V|v9Uc6۴U%{s/+Wz)?79-bɸF%vOۗ掴SL,"#Yk82W@&5Y1
"L,d{Y
:q
HO3V3h֕zЬ
3uan!~6Oƀ),ۖ::[Hec8c3*-{9_]?2=r)EBQP8oTӄhk-6s/
U&W-gsu"#Oؿ*G,cv֚{ AC1Y:'1K2zgLijzPk6*mrA1ҏ@$/māͳl9>ͅ'R072mېNn*oK~騟]wo6.Y+jp,5mY:LzaXy%zVceը$*ԅkl)%4
7dnnڗ2B3:iRZsMR p*Ȏ/E}9y|flꈝ&/#vrg uj}P
>\*=A,|
v]2[\t{YKp"PKh3ޢa
h7A$1| JdXS+//Q}gIQօM|Er7,fi\@q(c6>D5p9x_yKH-e^D_zAriq[J-0:n)uT_+HM{7c'#(ޣmVP{ALsN0~q^K75`22|I&k%323ɗW9aTfy&%ʉLfiTeY֯G
'-Kr4&8+*&ceiB9)N(7<ɨT&VD%Oa4URTmYZ<'p{ux&h^LiЏ l2LlѼSRf-'Z]hܓ[dP
y{HvY)2a_EU/ڣ"Ѐ*Q*E>_}mG^d*5ѢY¾X4. yP3 \$g;" ,IC:ޫzvpzj|V%^Ծ5As퉚lvЛPcCFkޚ+p`n{\%&!4i)L[h3PQ@1QpT5իM]-#wwQ(*q;d˻h>Psal[3W qR eW2oj~3bd2AyRE&2N`pT3YDZn Y͋rkt| jܖwCk/#V}Xp`t烱ðϧx,)6pr;i0^nlv#mZ>85d6wзbim01¹ CuĠ?n'n"!xu*
ʨ,h2;vƗY&\͆
5tl6
2Wt_#ڎ_nNnuŖ7`G@`o)65aì[ru5ĺ&sv}n+.0}R!N[efFCpdžʾ mhLE{RljZCvzw-oȈYC]ha~xkҵۻ6>|:)o
2I-ڹ3Bӄ|}M6 ;h6ɥ3F8s7eSp=:5*#)+*וYc%
{d$k_NA{ ê>s(Ӎ94XfOZs,u~}uUNb냓1fj%w |